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    • CD46 抗原（重組蛋白）

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW4147
      • 應(yīng)用 : 僅供科研使用
      • 保存條件 : 低溫保存
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    中文名稱： CD46 抗原（重組蛋白）

    英文名稱： CD46 Antigen (Recombinant Protein)

    相關(guān)類別：抗原

    儲(chǔ)    存： 冷凍（-20℃） 避光

    概    述

    Fusion protein corresponding to a region derived from 35-285 amino acids of human CD46

    技術(shù)規(guī)格

    Full name:

    CD46 molecule, complement regulatory protein

    Synonyms:

    MCP; TLX; AHUS2; MIC10; TRA2.10

    Swissprot:

    P15529

    Gene Accession:

    BC030594

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.