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021-54845833/15800441009
中文名稱：兔抗CASP10多克隆抗體
英文名稱： Anti-CASP10 rabbit polyclonal antibody
別 名： caspase 10 MCH4; ALPS2; FLICE2
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CASP10
反應(yīng)種屬： Human
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CASP10 |
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Immunogen: |
Synthetic peptide of human CASP10 |
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Full name: |
caspase 10 |
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Synonyms: |
MCH4; ALPS2; FLICE2 |
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SwissProt: |
Q92851 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer; Human ovarian cancer |
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IHC Recommend dilution: |
20-100 |
